Abstract: Abstract: The molecular technique was used in the molecular staging of lung cancer to find the occult micrometastasis of the tumor, and to forecast the metastasis and recrudescence of the tumor. The method was used for checking genetic mutations or protein expressions in the lymph node, blood andbone marrow of patients with cancer. It also can detect the occult focus which will not be found by ra-diological and histopathological techniques. Molecular Staging of cancer may be a important part of TNM staging of tumor. The article dissertates the concept of molecular techniques and the result inmolecular staging of NCLC. It indicates the predominance and deficiency of the molecular techniques in present study.