Abstract:
Objective :To evaluate the diagnosis and treatment of primary testicular nonsemino-matous germ cell tumors (NSGCT).
Methods :Sixty- eight cases of NSGCTs were analyzed. There were35 embryonal carcinomas, 11 teratomas, 3 yolk sac tumors, 6 choriocarcinomas and 13 mixed germ celltumors. The cardinal clinical manifestation was painless solid enlargement of the testis. Combined thera-py, including radical orchiectomy (RO), retroperitoneal lymph node dissection (RPLND) andchemotherapy, was given.
Results :Sixty-three patients have been followed up at 3 and 5 years. B-ul-trasound is better than CT in the diagnosis of NSGCT; on the other hand, CT is better than B-ultra-sound in the detection of metastasis to retroperitoneal lymph nodes. Survival rates are similar to reportsat home and abroad.
Conclusion :Combined therapy, including RO, RPLND and chemotherapy is sat-isfactory. Clinical staging is based on CT or B-ultrasound. Tumor markers are helpful for diagnosis,prognosis and monitoring the therapeutic effect of treatment on NSGCT.