Abstract: Objective: To summarize the experience and understanding of the instrumental anastomosis of intrathoracic esophagogastria after excision of inferior esophageal carcinoma or carcinoma of the gastric cardia. Methods: Retrospective analysis was conducted for 1555 cases with resection of inferior esophageal carcinoma or carcinoma of the gastric cardia who received postoperative esophagogastric anastomosis during a period from January 1990 to June 2005. Results: The mean operation time was 2 h and 40 min. After surgery, the incidence of slight postoperative bleeding at the stoma, anastomotic fistulae, anastomotic stricture, and gastroesophageal reflux was 1.54%, 1.03%, 2.06% and 7.07%, respectively. Aortic sinus fistulae at the stoma occurred in 9 cases within 3 months (0.58%), among which successful surgical hemostasis was achieved in 4 cases and death occurred in 5 cases. Conclusion: It is believed that the effect of intrathoracic esophagogastric end-to-side anastomosis, using a tubiform digestive-tract stapler, is reliable. The stapler is convenient for use in surgery, is easy to grasp and deserves popularization in its application. However, complications that cannot be ignored still occur, especiallytheaorticsinusfistulaeatthestomawhichisextremelyhazardousandrequiresspecialattention.