Abstract: Objective: To investigate the clinical characteristics, treatment and prognosis for patients with cervical cancer with distant lymph node metastasis after combination therapy. Methods: Data of 5 patients with distant lymph node metastasis of cervical cancer, from January 2000 to January 2006, were analyzed retrospectively. Results: Of the 5 patients, cervical adenocarcinoma was confirmed in 1, poorly differentiated squamous cancer (SqCa) of the cervix was confirmed in 3 and moderately differentiated SqCa of the cervix was confirmed in 1. There was no evidence of distant lymph node metastasis before combined treatments according to the MRI/CT scans. However, remote lymph node metastases were seen 1 to 24 months after the combined treatment, including paraaortic lymph node metastasis shown in 4 cases and a complication of supraclavicular lymph node metastasis in 2 cases. Four patients died after systematic chemotherapy and local three- dimensional conformal radiotherapy, with a mean survival rate of 15.3 months. One patient with uncontrolled recurrence achieved a survival time of 24 months. Conclusion: Supraclavicular and paraaortic lymph node metastases are both distant lymph node metastasis sites for patients with poorly- differentiated cancer of the cervix. Surgery combined with chemo- radiotherapy is needed for treating the patients. Positron emission tomography (PET) or single photon emission computed tomography (SPECT) is useful for diagnosis, follow- up and prognosis of the disease.