岳东升, 王长利, 张真发, 战忠利. 107例细支气管肺泡癌临床特征及预后分析[J]. 中国肿瘤临床, 2007, 34(9): 515-518.
引用本文: 岳东升, 王长利, 张真发, 战忠利. 107例细支气管肺泡癌临床特征及预后分析[J]. 中国肿瘤临床, 2007, 34(9): 515-518.
Yue Dong-sheng, Wang Chang-li, Zhang Zhen-fa et al, . Clinical Characteristics and Prognostic Analysis of 107 Patients with Bronchioloalveolar Carcinoma[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2007, 34(9): 515-518.
Citation: Yue Dong-sheng, Wang Chang-li, Zhang Zhen-fa et al, . Clinical Characteristics and Prognostic Analysis of 107 Patients with Bronchioloalveolar Carcinoma[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2007, 34(9): 515-518.

107例细支气管肺泡癌临床特征及预后分析

Clinical Characteristics and Prognostic Analysis of 107 Patients with Bronchioloalveolar Carcinoma

  • 摘要: 目的:分析探讨细支气管肺泡癌(BAC)的临床特点及预后因素。方法:对1990年1月~2000年12月于我院接受手术的107例细支气管肺泡癌的临床资料进行分析。结果:细支气管肺泡癌总体1年、3年及5年生存率分别为88.7%、64.8%和48.6%。单因素分析影响预后的因素为肿瘤直径(P=0.027)、支气管断端是否阳性(P=0.016)、TNM分期(P=0.000)、T分期(P=0.002)、N分期(P=0.000)、术后是否放疗(P=0.001);Cox回归多因素分析提示,TNM分期(P=0.000)和肿瘤直径(P=0.015)是独立的预后影响因素。结论:细支气管肺泡癌总体生存率优于其它非小细胞肺癌,影响其预后的因素主要为TNM分期和肿瘤直径。

     

    Abstract: Objective: To study the clinical characteristics and prognostic factors of bronchi-oloalveolar carcinoma. Methods: Clinical data of 107 inpatient cases seen in The Cancer Hospital of Tianjin Medical University, from 1990- 2000, were retrospectively reviewed. Results: The overall 1-year survival rate was 88.7%, the 3- year survival rate was 64. 8%, and the 5- year survival rate was 48.6%. The main prognostic factors were tumor diameter (P=0.022), bronchial stump (P=0.016), TNM stage (P=0.000), T stage (P=0.002), N stage (P=0.000), and postoperative radiotherapy (P=0.001). Cox regression analysis suggests that TNM stage (P=0.000) and tumor diameter (P=0.015) are independent factors affecting prognosis. Conclusions: The overall survival rate of BAC was superior to other NSCLC.TNM stage and tumor diameter are independent factors affecting the prognosis of BAC.

     

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