Abstract: Objective: To study the pathological type and therapy of intraductal papillomary tu-mor. Methods: To review 106 cases female intraductal papillomary tumor in our department and inves-tigate their clinic symptom 、 pathological type and therapy way. Pathological type criteria are followedas the criteria which were made by WHO in 2003. Results: Nipple bloody discharge is most common,56.6%(60/106), secondly breast lump, 30.2%(32/106) and thirdly both, 13.2%(14/106) among 106 casesfemale intraductal papillomary tumor clinic symptoms. There are 38 cases central intraductal papilloma(35.8%), 42 cases intraductal papilloma(39.6%), 7 cases intraductal papilloma with atypical hyperplasia(6.6%), 19 cases invisive papillomary carcinoma (17.9%) among pathological types. The rate of malig-nant disease in breast is 54.3% among intraductal papilloma over 50 years, 40.4% in secondary ductabove, 46.5% with microcalcification, 55.2% with the past papilloma,all having statistical significance.Therapy ways include: 1) Duct lesion and surrounding tissue excision; 2) Big section 、 dimension or totalbreast excision; 3) Modified radical mastectomy. Conclusion: The key to success of operation is preciselocation preoperation. The carcinogenesis rate is high in papilloma which lesions lie above secondary duct or accompanying with calcification or having past papilloma. The treatment principle is surgical excision, and all patients should be given closely observation and regular follow-up visits.