Abstract: Objective : To investigate the value of various postprocessing techniques in the detec-tion of bladder cancer by MDCT and to propose an improved protocol for CT examination in bladder cancer cases. Methods : MDCT, including unenhanced scans and contrast-enhanced scans (late artery-phase, equilibrium-phase, and excretory-phase), was performed with an adequately distended bladder for 34 patients who were clinically suspected of bladder cancer. On the MPR and CTVE images gener-ated from the volumetric data of the different phases, various locations of the bladder wall were ob-served in turn. The number, location, and size of the lesions were recorded. The interpretations of the MPR and CTVE images were compared. Results : All patients underwent surgery within 1 week after CT scanning, and 58 bladder cancers were found including two combined tumors of the ureter. The de-tection rate of unenhanced MPR, late artery-phase/equilibrium-phase MPR, excretory-phase MPR, CTVE, and the combination of MPR and CTVE images were 70.7%, 86.2%, 89.7%, 87.9%, and 100%, respectively. The detection rate of unenhanced MPR was lower than that of the other means (P<0.05). The detection rate of the combined MPR and CTVE images was higher compared to that of the other methods (P<0.05). There was no significant difference in the detection rate among the late artery-phase/ equilibrium-phase MPR, excretory-phase MPR and CTVE images (P>0.05). Conclusion: For detecting bladder tumors, it is best to use CT examination that covers the entire urinary system. The combination of MPR and CTVE images generated from the equilibrium—phase and excretory-phase by MDCT data can provide comprehensive information for the detection of bladder cancer.