Abstract: Bone diseases would be developed in most patients with multiple myeloma (MM) during the course of disease, which severely jeopardize the quality of life and survival rates of the patients. Standardized chemotherapy, targeted therapy and bone-modifying agent compose the fundamental treatments for MM, while surgical treatments play a critical role in the treatment for acute complications of bone diseases (e.g. pathological fracture, spinal instability, spinal cord compression). The Bone Tumor and Bone Metastasis Committee of Chinese Anti-Cancer Association proposes the " Expert consensus on surgical treatment of multiple myeloma bone disease". This consensus addresses several clinical problems (e.g. timing for surgical treatments, indications for operations, surgical options for lesions of different locations, and multi-modality treatments) and provides recommendations with categories of evidence and consensus. The Committee hopes that this consensus can provide the most effective references for practitioners of oncological orthopaedics in order to achieve the best outcomes for patients. But this consensus provides only academic recommendations and should be adapted to individualized treatments during clinical practice.