Abstract: Glioma is the most common primary intracranial tumor in adults characterized by high morbidity and recurrence rates. It has a serious impact on the quality of life of patients, threatening their lives and presenting a heavy burden to patients, their families, and the society. Currently, the classification of gliomas is becoming clearer, and the traditional and advanced diagnosis and treatment strategies for glioma are gradually becoming more precise and standardized. For the Chinese population, the guideline combines the long-term study results of glioma in Chinese Mainland and latest international progresses, integrating traditional strategies with new precision diagnosis and treatment strategies and forming an integrative clinical diagnosis and treatment guideline suitable for Chinese doctors and patients with glioma. It will enable relevant domestic practitioners to maintain with the times, improve the integrative diagnosis and treatment of glioma in the country, and eventually provide better service for Chinese patients with glioma.