Abstract:
Objective To evaluate the diagnostic performance and safety of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for biliary lesions and to investigate the factors influencing its accuracy.
Methods A retrospective analysis was performed on the clinical data of patients who underwent EUS-FNA at Chengdu Third People's Hospital between January 2021 and December 2023 for suspected malignant biliary strictures or masses, including 22 males and 19 females, with a mean age of 65.9 (35.0–89.0) years. Diagnostic performance (sensitivity, specificity, positive predictive value, negative predictive value, and accuracy) and factors influencing these outcomes were evaluated.
Results The overall sensitivity of EUS-FNA for diagnosing biliary lesions was 85%, with a specificity of 100%, positive predictive value of 100%, negative predictive value of 33%, and accuracy of 86%. The use of a 25G needle and the presence of solid masses were significant factors influencing the diagnostic accuracy of EUS-FNA. In contrast, the puncture site did not impact diagnostic performance. No EUS-FNA-related adverse events were observed during the follow-up period.
Conclusions EUS-FNA is highly accurate and safe for the diagnosis of biliary lesions. The diagnostic accuracy of EUS-FNA significantly improves when using a 25G needle and in the presence of solid biliary masses.
下载: