2010年至2024年淮河流域山东省沂源县上消化道癌早诊早治项目情况分析

Analysis of early diagnosis and treatment project for upper digestive tract cancer inYiyuan County, Huaihe river basin from 2010 to 2024

    摘要
  • 摘要:
    目的 分析2010年至2024年淮河流域山东省沂源县上消化道癌早诊早治项目的筛查及随访资料，了解筛查结果及变化趋势。
    方法 数据来源于淮河流域癌症早诊早治项目数据管理系统，山东省沂源县项目点2010年至2024年48 205人的筛查数据，采用χ2检验比较检出率、早诊率和治疗率组间差异；用Joinpoint 5.0.2软件分析变化趋势。
    结果 2010年至2024年总体高危率为69.58%；男性高危率为68.25%，女性为70.77%，女性高危率高于男性（χ2=35.907，P<0.001）。2010年至2024年人群高危率的变化虽有下降，但差异无统计学意义（AAPP=-3.65%，P=0.514）。从年龄分布来看，高危人群占比最高的年龄组是50～54岁，阳性检出率占比最高的年龄组是65～69岁。总阳性检出率为1.07%、总早诊率为70.46%、总治疗率为95.02%；其中胃癌阳性检出率为0.96%、食管癌为0.11%，胃癌阳性检出率高于食管癌（χ2=177.92，P<0.01）。食管癌早诊率为48.28%、胃癌为73.02%，胃癌早诊率高于食管癌（χ2=7.65，P<0.01）。
    结论 山东省沂源县胃癌风险率较高，实施胃癌筛查对于疾病防控至关重要，下一步宜加大干预措施，提升项目筛查效果、降低胃癌的发病率和死亡率。

     

    Abstract:
    Objective  Analyze the screening and follow-up data of the early diagnosis and treatment project for upper gastrointestinal cancer in Yiyuan County from 2010 to 2024, and understand the screening results and trends.
    Methods Data were sourced from the early diagnosis and treatment program database of the Huaihe River Basin Cancer Early Diagnosis and Treatment Program, covering 48,205 cases in Yi Yuan County from 2010 to 2024. The χ² test was used to compare the differences in detection rates, early diagnosis rates, and treatment rates among groups, while Joinpoint 5.0.2 software was employed to analyze the trends.
    Results The overall high-risk rate from 2010 to 2024 is 69.58%; The high-risk rate for males is 68.25%, while for females it is 70.77%. The high-risk rate for females is higher than that for males (χ2=35.907, P<0.001). Although there was a decrease in the high-risk rate of the population from 2010 to 2024, the difference was not statistically significant (AAPP=-3.65%, P=0.514). From the perspective of age distribution, the age group with the highest proportion of high-risk population is 50-54 years old, and the age group with the highest proportion of positive detection rate is 65-69 years old. The total positive detection rate was 1.07%, the total early diagnosis rate was 70.46%, and the total treatment rate was 95.02%; The positive detection rates of gastric cancer and esophageal cancer were 0.96% and 0.11%, respectively. The positive detection rate of gastric cancer was higher than that of esophageal cancer (χ2=177.92, P<0.01). The early diagnosis rate of esophageal cancer is 48.28%, and the early diagnosis rate of gastric cancer is 73.02%. The early diagnosis rate of gastric cancer is higher than that of esophageal cancer (χ2=7.65, P<0.01)
    Conclusions The risk rate of gastric cancer in Yiyuan County is high, so it is necessary to carry out gastric cancer screening. In the next step, intervention measures should be increased to improve the screening effect of the project and reduce the incidence rate and mortality of gastric cancer.

     

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