Abstract:
Objective:To evaluate the survival status and prognosis factors of primary bronchogenic carci -noma in the elderly. Methods:A total of450 cases of lung cancer in the elderly seen in our hospital between January 2002 and January 2007 were retrospectively reviewed. Patient survival and prognostic factors were analyzed. Results: The 1- and 3-year overall survival rates were 52.12% and 57% , respectively. The1- and 3-year survival rates were higher in treated patients than in untreated patients ( 52.8%:10.18%;17.26%:0, P<0.05). Multivariate analysis showed that patients' nation, payment methods, pre-treatment performance status (PS) score, weight loss, metastasis, pathology, staging and treatment were related to long-term survival rate. The 1- and 3-year survival rates in patients treated with surgery was higher than in those who received che -motherapy and supportive care (P<0.05). Single factor analysis revealed that gender, smoking index, compli -cations, hemoglobin level, and albumin level were not correlated with survival rate. Multi-factor analysis showed that pre-treatment PS score, stage and weight loss were independent prognostic factors for lung can -cer in the elderly. Conclusion:Treatment can improve the survival of lung cancer in the elderly. For those with early stage lung cancer, surgery can achieve better results than chemotherapy and supportive care. Pre-treat-ment PS score, stage, and weight loss are independent prognostic factors.