Abstract: Objective:To investigate the clinical value of laparoscopic partial nephrotomy.Methods:Fifty-eight patients were treated with laparoscopic surgeries, of which43had renal tumors, 14had hamartoma and1 had Renin tumor. The di -ameter of tumors ranged1-6 cm, (2.5 ± 1.5cm on average). Surgeries were performed through retroperitoneal route: expos -ing the tumor and renal artery; dragging the renal artery with block folder; resecting the tumor with 1cm normal renal tissue by Ultracision; compressing the wound surface with homeostasis carcasses and suturing it with line; relaxing the tube;tak-ing out the tumor tissue and finishing the surgery. Results: Three cases were turned to open surgery because of tumor of large size or multi-artery or bleeding. The surgical duration ranged from 65to 200 min, with an average of 95± 43min. The introperative blood loss was 20to 1500mL approximately, with an average of 140 ± 60mL. The artery block time was 30-45 min in the first10cases and 8-28min in the other cases. Intestinal tract function recovery time and the postoperative hospi-tal stay were 12-36hours and 10-14days, respectively. The patients must stay in bed for 7 to 10days. During follow up of 6 to 48months, patients' renal blood flow showed no obvious abnormal features,1 case had incision metastasis, 1 case had renal portal lymph node metastasis, 2 cases had pathological positive margin and were treated with open radical resec -tion. Conclusion:The laparoscopic enucleation of the renal tumors is a non-invasive, safe and effective therapy and can be considered as the first choice for patients with exophytic malignant tumors smaller than 4cm and benign tumors of larger size.