<sup>125</sup>I 粒子植入术治疗门静脉癌栓40例近期疗效观察

¹²⁵I 粒子植入术治疗门静脉癌栓40例近期疗效观察

摘要: 目的：探讨CT导向下¹²⁵I 粒子植入治疗门静脉癌栓的临床价值和操作流程。方法：选取40例原发性肝细胞癌伴门静脉癌栓患者，采用TPS 计算布源，在CT导向下将¹²⁵I 粒子植入瘤灶内，采用（2.2～3.3）× 10⁷Mq活度的125I 粒子多层面播植。结果：40例患者中癌栓完全缓解18例（45.0%），部分缓解22例（55.0%），总有效率100% 。所有患者均未发生手术相关严重并发症。结论：CT导向下¹²⁵I 粒子植入治疗门静脉癌栓近期效果好，安全性高，创伤小，并发症发生率低。

Abstract: Objective: To investigate the clinical value of CT-guided ¹²⁵I radioactive seed implantation in treating portal vein tumor thrombus. Methods:A total of 40hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus were collected. Under CT guidance, ¹²⁵I seeds of 2.2 × 10⁷ to 3.3 × 10⁷ Mq were implanted into the metastatic lymph nodes accord-ing to TPS. Results: Of the 40 patients, 18 cases (45.0% ) achieved complete remission (CR), and22 cases (55.0% ) achieved partial remission (PR). The overall response rate was 100 % . No serious complications were observed.Conclusion: CT-guided ¹²⁵I radioactive seed implantation is effective and safe in treating portal vein tumor thrombus with minimal damage and few complications.