胸腺类癌的CT表现并文献复习

CT Examination of Thymic Carcinoid and Review of Literature

  • 摘要: 探讨胸腺类癌的CT表现特征。方法:回顾性分析8例经病理证实的胸腺类癌患者的临床资料和CT表现,并结合相关文献复习。结果:胸腺类癌临床表现无特异性。CT上表现为肿瘤体积较大;密度均匀(2/8)或不均匀(6/8),稍低于或等于肌肉密度,内部可见低密度坏死或囊变区(6/8),均未见高密度钙化灶;增强扫描肿瘤呈明显较均匀强化(2/8)其中1例内部见小线状强化血管影,轻中度不均匀强化(5/8)其中1例内部见小线状强化血管影,明显不均匀强化(1/8);肿瘤包膜不完整,与周围组织结构分界不清,易沿血管间隙侵袭性生长,压迫、包绕或侵犯邻近纵隔大血管(5/8),心包侵犯(1/8);淋巴结转移(4/8)或胸膜、肺脏、肝脏、骨转移(4/8)常见。结论:胸腺类癌是一种罕见的前纵隔肿瘤,CT表现具有一定的特征性,密度不均匀,可见坏死、囊变,边界不清,增强扫描轻中度不均匀强化,易发生淋巴结、肺脏等远处转移。CT可以提示诊断并帮助确定手术方案,确诊仍依赖于病理。

     

    Abstract:  To investigate the computerized tomography ( CT ) appearances of thymic carcinoid. Methods: The clinical data and CT appearances of 8 pathologically confirmed thymic carcinoid cases were retrospectively analyzed, together with a review of literature. Results: Thymic carcinoids have not been characterized in clinical findings. Carcinoid syndrome was found in one case. On plain CT, tumors were usually of isodense slightly hypodense compared to muscle tissue. The density of the tumors was homogeneous ( 2/8 ) or heterogeneous ( 6/8 ), and showed necrosis or cystic degeneration ( 6/8 ). After injection of the contrast medium, the tumors showed marked homogeneous enhancement ( 2/8 ), slight or moderate enhancement ( 5/8 ), and apparent heterogeneous enhancement ( 1/8 ). Moreover, linear enhancement of the blood vessels was observed in the tumors of two cases. The tumor margins were usually ill-defined, extending into the vessel spaces, and often invading or compressing the vessels ( 5/8 ) or pericardium ( 1/8 ). Lymph node metastases were common in thymic carcinoids ( 4/8 ), and distant metastases were frequently observed in the pleurae, lung, bone, and liver ( 4/8 ). Conclusion: Thymic carcinoid is a rare tumor in the anterior mediastinum. The CT findings reveal definite characteristics. Tumor density is heterogeneous with necrosis or cystic degeneration and slightly or moderately enhanced after bolus injection of contrast medium. The CT image can indicate the diagnosis of thymic carcinoid and is helpful for surgical planning. However, the final diagnosis still depends on histopathology.

     

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