胰十二指肠切除术联合周围脏器切除在进展期胃癌治疗中的应用

Pancreaticoduodenectomy with Resection of Adjacent Organ in Advanced Gastric Cancer Therapy

    摘要
  • 摘要:
      目的  总结进展期胃癌行根治性胰十二指肠切除术(PD)联合周围组织器官切除在原发及复发胃癌治疗中的的经验及疗效。
      方法  回顾性分析2002年10月至2006年10月收治的5例原发胃癌或胃癌术后复发行胰十二指肠切除术或联合周围脏器切除病例, 其中3例为原发胃癌, 2例为胃癌术后复发。
      结果  1例患者因腹腔感染及腹腔出血于围手术期内死亡, 1例出现胰瘘, 经保守治疗好转后出院。4例患者均获得12个月以上生存, 平均生存期22.2个月。
      结论  胰十二指肠切除术联合周围脏器切除治疗胃癌有一定风险, 但如合理应用, 可获得较好临床疗效。

     

    Abstract:
      Objective  To summarize the treatment experience and effect of pancreaticoduodenectomy (PD) combined with resection of adjacent organs in primary and recurrent gastric cancer.
      Methods  Data from 5 patients with gastric cancer who underwent PD alone or with resection of adjacent organs from October 2002 to October 2006 were retrospectively analyzed. Of the 5 cases, 3 were primary gastric cancer and 2 were recurrent gastric cancer patients.
      Results  One patient died in the perioperative period because of abdominal infection and abdominal bleeding, and 1 case of pancreatic fistula was cured after conservative treatment. Four patients survived over 12 months, and the mean survival was 22.2 months.
      Conclusion  PD with resection of adjacent organs in the treatment of gastric cancer presents risk; however, the procedure can improve its clinical efficacy if properly applied.

     

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