营养支持小组对于食管癌同步放化疗患者作用的研究

Roles of nutrition support team for esophageal carcinoma patients treated with concurrent chemoradiotherapy

    摘要
  • 摘要:
      目的  研究营养支持小组(NST)的参与是否对接受同步放化疗食管癌患者有益。
      方法  2012年6月至2013年12月因食管癌拟行放化疗患者40例入组, 随机分为NST组和常规治疗组进行营养干预, 观察放疗结束时患者营养状况、并发症发生率、治疗完成率、住院时间及住院费用。
      结果  NST组患者放疗结束时各项营养及血液指标均优于常规治疗组(P < 0.05), 并发症发生率低于常规治疗组(P < 0.05), NST组全部按计划完成治疗, 常规治疗组5例出现中断或延迟(P < 0.05), NST组住院时间平均缩短3.8d(P < 0.05), 住院费用减少了6 300元/人次(P＞0.05)。
      结论  对于食管肿瘤放化疗患者, 营养支持小组的参与有利于维持患者的营养状况, 提高患者的治疗顺应性, 缩短住院时间, 降低住院费用。

     

    Abstract:
      Objective  To investigate whether the nutrition support team (NST) benefits esophageal carcinoma (EC) patients who are concurrently undergoing chemoradiotherapy.
      Methods  Between June 2012 and December 2013, 40 EC patients undergoing chemoradiotherapy were divided into the NST group and routine treatment (RT) group, with 20 patients in each group. At the end of chemoradiotherapy, the nutritional status, incidence of complications, and completion rates of radiotherapy were evaluated. The length of hospital stay (LOS) and cost were also compared between the two groups.
      Results  The nutrition and blood parameter values of the NST group were better (P < 0.05) than those of the RT group. The incidence of complications was lower in the NST group (P < 0.05) than that in the RT group. In addition, all patients in the NST group achieved the treatment plan, whereas five of the patients in the RT group interrupted or delayed the plan (P < 0.05). The average LOS decreased by 3.8 d (P < 0.05), and the hospitalization costs were reduced to 6300 RMB person-times (P＞0.05) for the patients of the NST group.
      Conclusion  NST could maintain the nutritional status and improve the treatment compliance and tolerance of EC patients undergoing chemoradiotherapy, thereby shortening the LOS time and reducing the costs.

     

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