Abstract: objective:To investigate the clinical features and prognosis of pinealoblastoma in children. Methods:The clinical data of 10 patients with pinealoblastoma were retrospectively analyzed. These patients were admitted to the Department of Radiation Oncology, Beijing Shijitan Hospital, Capital Medical University from December 2011to December 2015. Results:This study included 10patients, with 8 males and2 females, with a median age of 7 years. Of the 10patients, 5 underwent gross total resection and 5 underwent sub-total resection. The 10patients were exposed to craniospinal irradiation after surgery. The median doses of craniospinal irradiation and tumor bed were 30. 6 (25. 5- 36) Gy and 55. 8 (50. 4- 60) Gy, respectively. Of the 10patients, 4 underwent chemotherapy 1 month af-ter radiotherapy. The median follow- up period was 16. 5 (1. 5- 49) months. The 10patients survived. No local and distant recurrences were observed.Conclusion: Pinealoblastomas are rare, malignant, and pineal regional lesions that can metastasize along the neuroax -is. Surgery combined with adjuvant radiotherapy and chemotherapy should be applied to patients with pinealoblastoma. Prognosis is also favorable.