食管癌放疗技术及放疗方式研究进展

Research progress on radiotherapy of esophageal carcinoma

  • 摘要: 食管癌(esophageal carcinoma)是最常见的消化道肿瘤之一,其发病率及死亡率均较高。局部晚期食管癌经手术治疗后极易复发,预后不良,以手术为基础的综合治疗在降低食管癌复发率、提高患者生存等方面发挥着重要作用。放射治疗作为食管癌综合治疗的重要组成部分,从传统的二维放疗到如今的三维适形放疗、调强适形放疗、图像引导放疗、容积弧形调强放疗,其放疗技术经历了较大的发展,一定程度上改变了以往放疗靶区剂量不足、对器官造成危害的剂量过高等缺陷,提高了放疗精确度。目前临床在术前放疗、术后放疗以及放化疗结合等放疗方式上有了一些新的认识。本文就食管癌放疗技术及放疗方式的研究进展进行综述。

     

    Abstract: Esophageal cancer is one of the most common malignant tumors in the digestive tract. Its morbidity and mortality rates are high. Local advanced esophageal cancer relapses easily after operation and has a poor prognosis. Operation- based comprehensive treatment plays an important role in reducing the recurrence rate and increasing the survival rate. Radiotherapy is an important part of comprehensive treatment. From conventional radiotherapy two dimeusional conformal (2DCRT) to three dimensional conformal ra -diotherapy (3DCRT), intensity modulated radiation therapy (IMRT), image guide radiation therapy (IGRT), and volumetric modulated arc therapy (VMAT), radiotherapy technologies have experienced significant development. This development optimized the dose distri -bution and improved the accuracy of radiation. It has also provided a new understanding of the methods of radiotherapy, such as pre-operation radiotherapy, post operation radiotherapy, and radiotherapy combined with chemotherapy. The progress of radiotherapy re-search on esophageal cancer is reviewed in this paper.

     

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