Objective  To identify risk factors for positive surgical margin after laparoscopic radical prostatectomy.

  Method  The study retrospectively analyzed the records of 177 patients with prostate cancer who eventually underwent laparoscopic radical prostatectomy from January 2016 to December 2017 in Peking University First Hospital. Age, prostate volume, prostate-specific antigen (PSA) before needle biopsy, number of positive cores, positive percentage of needle biopsy and biopsy, and postoperative Gleason scoreand pathological stage were analyzed.

  Results  The overall positive surgical margin rate was 32.2% (57/177). Age, prostate volume, PSA before needle biopsy, positive percentage of biopsy, and postoperative Gleason score were not significantly different (P>0.05). The study demonstrated significant differences between the number of positive cores, positive percentage of needle biopsy, and pathological stage (P < 0.05). Multiple logistic regression revealed that the pathological stage was an independent factor affecting the positive surgical margin rate (odds ratio, 1.616; 95% confidence interval, 1.062-2.459).

  Conclusions  The number of positive cores, positive percentage of needle biopsy, and pathological stage significantly correlated with a positive surgical margin. The postoperative pathological T stage is an independent factor affecting positive surgical margins.