Abstract: Breast reconstruction is an essential part in the comprehensive management of breast cancer. The clinical application of patches (e.g., acellular dermal matrix, ADM) is the most impactful innovation in implant breast reconstruction in recent years. The wide application of patches in implant breast reconstruction promotes the development of immediate prosthetic reconstruction, improves the aesthetic outcomes of reconstructed breasts, and avoids additional donor tissue damage caused by autologous flap breast reconstruction. At present, patches used in breast reconstruction are mainly ADMs, bovine pericardial patches, and TiLOOP, which are widely used because of their good histocompatibility and tissue defect repair ability. This article reviews the applications and research statuses of these patches.