慢性阻塞性肺疾病与肺癌危险性关系的探讨

A Study of the Relation between Chronic Obstructive Pulmonary Diseases and the Risk of Lung Cancer

  • 摘要: 目的: 分析慢性阻塞性肺疾病(chronic obstructive pulmonary diseases,COPD)与肺癌危险性的关系. 方法: 对西安地区1999年至2001年肺癌组248例及对照组263例进行对照分析. 结果: 有慢性支气管炎、肺气肿的COPD患者,肺癌发生的CORD值明显升高,分别为2.25和2.33.当FEV1<70%时,肺癌的OR值为2.28. 结论: 有COPD病史的患者,肺癌发生的危险性明显增高.肺功能的损伤增加了肺癌发生的危险性.

     

    Abstract: Objective :To analyze the relationship between chronic obstructive pulmonary disease (COPD) and the risk of lung cancer. Methods :The analysis was based on the data of a case control study conducted during the period from 1999 to 2001 in Xi'an, China, and was evaluated by the odds ratio (OR). Results :The patients with COPD had an increased risk of lung cancer, OR=2.25 for Bron- chins and OR=2.33 for Emphysema. When FEV, was lower than 70%, the risk of lung cancer increased (OR=2.28). Conclusions :The risk of lung cancer increases in the patients with a history of COPD, and the impairment of lung function is suggested to increase the risk of lung cancer.

     

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