Abstract: Objective :To evaluate the diagnosis and treatment of the carcinosarcoma in urine and reproduction system. Methods :Surgical operations were performed in all the six cases. Results :All were proved the carcinosarcoma by pathology and immunohistochemistry after operation, i.e. 4 cases died of carcinomatous deseases, one was not followed up and the other one case has been alived for 28 months by now. Conclusions :The carcinosarcoma in urinary and genital system is rare clinically and is difficult the diagnosed preoperatively. The immunohistochemistry is helpful for diagnosis of the disease. It is malignant with bad prognosis and early radical resection will be the best treatment.