Abstract: Objective :To study the clinicopathologic features and treatments of low-grade myofi-brosarcoma (LGMS). Methods :The clinical and pathologic features of 9 cases with LGMS were analyzed using immunohistochemistry. Results : All patients were treated surgically, among which three of them were initially treated by wide excision. The tumor cells, with eosinophilic cytoplasm and tapered nuclei, were diffusely strong positive for SMA and MSA. Follow-up in 7 patients (median:) revealed recurrence in two cases 5 months and 7 years after local excision, and further recurrence and tongue metastases in the latter one 6 months after the re-excition. Conclusions : It has been confirmed in this research that LGMS is a low-grade malignant tumor, which can be recognized at light microscopy. The clinical significance is to avoide confusion with psuedosarcomatous conditions. Complete surgical resection and close follow-up are both necessary in the treatment to avoid recurrences.