Abstract:
Objective : To evaluate clinicopathological difference in varying stage of patients with mucinous gastric carcinoma (MGC) and to study clinico -pathological characteristics, which influenced the prognosis of MGC.
Methods : A total of 149 cases with MGC were admitted for treatment from January 1982 to December 1997. Their clinicopathological examination and prognosis were analyzed.
Results : Infiltration of serosa occurred easily in the patients with MGC (intermediate and advanced stage S
2+S
3: 67.5%), and MGC had stronger infiltration( I + II stage T
36.2%; III + IV stage T
3 44.4%). Inplantation of peritoneum occurred easily in intermediate and advanced stage (P
2+P
3: 30.7%). Metastasis of lymph occurred easily in intermediate and advanced stages (N
1+N
2 80.3%); The rate of radical resection in early stage was higher than it in intermediate and advanced stage (P<0.005). Survival rate for five years in early stage was higher than it in intermediated and advanced stages. There was a significant difference between early stage and another two stages.
Conclusion : Biological action is different in every stage of Mgc . Bad prognosis is related with the time of correct diagnosis, infiltration of serosa,metastasis of lymph node and a lower rate of radical resection.