Abstract:
Objective: To evaluate the effect of body mass on survival and morbidity of the patients with FIGO Stage Ib cervical cancer treated with radical hysterectomy. Methods: Medical records from all patients with FIGO (1995) stage IB cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy (RH + PLND), from 1987 to 1997, were retrospectively reviewed. According to body mass index (BM), the 87 cases with stage Ib cervical cancer were divided into three groups: BM-S in 23 cases (BMI<20), BMI-Min 48 cases(20≤BMI<27)and BMI- L in 16 cases (BMI≥27). Data collected included patients, age, pathological type, tumor size, degree of differentiation, depth of cervical invasion (DCI), lymph node metastasis, operating time, estimated blood loss, transfusion, and follow- up data.Results: There was no significant differences in age, DCI, or pelvic node metastasis, cell type, cell differentiation and tumor size. The five-year disease-free survival was 64.3% for BMI- S, 87.9% for BMI-M and 91.3% for BMI- L,respectively. Significant differences were observed between BMI- S and BMI-M, as well as BMI- S and BMI-L. DCI of group BMI-S was also significantly different from other two groups (P<0.05). Pelvic node metastasis (P<0.05), tumor size (P<0.01) and BMI- S (P<0.01) were independent poor prognostic indicators. Conclusion: Low BMI is a poor predictor for survival of the patients with FIGO stage Ib.