Abstract: Objective: To study the clinicopathological characteristics, the procedure of diagnosisand treatment, as well as the related factors influencing prognosis of remnant gastric cancer.Methods:The clinicopathological data and prognoses of 45 cases with remnant gastric cancer were analyzed ret-rospectively.Results: A total of 28 lesions were located at the stomas, among which 9 were at cardiaand 8 at other locations. In the study there were 19 cases of radical resection, among which 16 werepalliative resection, 8 exploring operations and 1 anatomasis of remnant stomach and jejunum per-formed. The histology types of these patients showed that there was 1 cases with non-differentiatedadenocarcinoma, 36 with poorly-differentiated adenocarcinoma, 7 moderately-differentiated adenocarci-noma and 1 well-differentiated adenocarcinoma. The 1-, 3-, 5-year survival rate of the patients withradical resection were significantly better than those with palliative resection (100% vs 62.5%, 78.8%vs 25% and 47.2% vs 0, P<0.05, repectively). All cases without resection died within 2 years. The 5-year survival rate for Stage Ⅰ, Ⅱ, Ⅲ, and Ⅳ was 100%, 75%, 17.8% and 0, respectively (P<0.05).Conclusion: The remnant gastric cancer prevalently occurs in male patients 10 years later after Bir-roth II gastrectomy. The prognosis of remnant gastric cancer has a close correlation with pTNM stageand with the probability of the radical resection.