Abstract: Objective: To investigate the effect of liver resection and intraoperative chemotherapy for rupture of hepatocellular carcinoma after transcatheter hepatic arterial embolization(TAE). Methods:Emergent TAE was performed in 27 cases of rupture of hepatocellular carcinoma, and the patients re-ceived operation within 3-14 days. Results: In 27 cases, liver function grade A was found in 5 cases, Bin 14 cases and C in 8 cases. The overall TAE hemostasis was achieved successfully in 100% cases 。All the patients were tread by late resection tumor, including hemihepatectomy in 9, middle lobectomyin 2, partial hepatectomy in 9, tumor resection in 1, dealt with palliative resection in 6, and intraperi-toneal hyperthermic chemotherapy, hepatic arterial and portal vein catheterization intraoperative chemotherapy were used when operation. Mortality of operation were 3.7%, over-all survival and tumorfree rates of 1, 3, 5 years were 80.1% and 65.4%, 68.4% and 42.1%, 27.3% and 18.2%. Conclusion:liver resection and comprehensive treatment followed TAE are the effective treatment in patients with rupture of hepatocellular carcinoma.