Pleomorphic Xanthoastrocytoma: Clinical Analysis of 8 Cases
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摘要: 目的:探讨多形性黄色瘤型星形细胞瘤患者的临床特征及治疗。方法:回顾8例多形性黄色瘤型星形细胞瘤患者的临床资料。结果:患者平均年龄23.7岁,肿瘤位于大脑半球。临床表现主要以癫痫起病。最后确诊主要靠病理学。显微手术全切5例,大部分切除3例,放疗3例,放化疗2例。随访10个月～5年,6例存活,癫痫及头痛得到控制,2例复发,1例复发死亡。结论:多形性黄色瘤型星形细胞瘤是一个相对良性肿瘤,癫痫发作是最常见的症状,治疗上应手术全切,对术后有残余、复发或间变者可给予放疗,预后相对良好。
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关键词:
- 多形性黄色瘤型星形细胞瘤 /
- 癫痫 /
- 手术 /
- 诊断
Abstract: Objective: To study the clinical characteristics and treatment of the patients with pleomorphic xanthoastrocytoma. Methods: The clinical data of 8 patients with pleomorphic xanthoastrocytoma were retrospectively analyzed. Results: The average age of the patients was 23.7 years old. Tumors were located in the cerebral hemisphere and the epileptic seizure was the major clinical manifestation for the tumors. The final diagnosis was dependent on pathological examination. The tumors were totally removed in 5 cases, subtotally in 3 and were treated with radiotherapy and/or chemotherapy in 5. All patients were followed up for 10 months to 5 years. Seizure and headache control were quite satisfactory: In the follow-up, 6 cases were survivals, 2 were relapses and 1 dead. Conclusion: Pleomorphic xanthoastrocytoma is relatively a benign tumor. Epileptic seizure is its main symptom. Radiotherapy should only be used in cases of residual tumor, relapse and malignant degeneration. The outcome of pleomorphic xanthoastrocytoma is usually good.-
Keywords:
- Pleomorphic /
- Xanthoastrocytoma /
- Epilepsy /
- Surgery
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