Abstract: Objective: To identify independent prognostic factors after surgical operation on pa-tients with gastric cancer. Methods: A total of 814 patients with gastric cancer, treated surgically from October, 1995 to April, 1999, were studied by univariate and multivariate analysis. Results: Of the 814cases, the 1-year, 3-year and 5-year overall survival rate was 71.87%, 45.33% and 40.05%, respec-tively. The univariate and multivariate analysis showed that five type of factors, such as Borrmann types, radical gastrectomy, way of resection, pathological type and TNM staging, were taken as the ma-jor independent prognostic factors. Conclusions: To improve the survival rate of gastric cancer, the reasonable plan of gastrecomy should be drawn up and the synthetic treatment around surgery should be performed basing on biological characteristics of each patient with the TNM clinical stage and Bor-rmann type, etc.