Abstract: Objective :To investigate the clinical features, the operative type and therapeutic-effi-cacy of adenocarcinoma salivary glands. Methods : Thirteen cases of salivary glands adenocarcinomawere reviewed and pathologic diagnosis was based on the WHO Classification. The clinical featureswere retrospectively analyzed and followed-up for prognosis. Results : Parotid gland was the most com-mon location of salivary adenocarcinoma. In the 13 cases, the average age of onset was 49.6, with amale preponderance. The median survival time, 3-year and 5-year survival rate was 8.5years, 83.3%,and 66.7%, respectively. Conclusions :The male patients predominate in the incidence of adenocarci-noma salivary glands, with parotid as the predilection site, surgical operation as the main treatment,complete initial-operation as the key of the treatment.Individualization is needed in the regimens. Themortality occurs mainly within 6 years after operation, after which the survival time significantly pro-longs.