Abstract: Objective :To assess the correlation between the sensitivity of some chemotherapeuti-cal agents in vitro and the effective rate of clinical treatment. Methods :Seven chemotherapeutical a-gents and 6 combined regimens were used to test the inhibition ratio for 70 cases with ovarian epithelialcarcinoma using MTT assay in vitro. Results : The effective rates for the agents and combined regimenswere 6.25%~51.43% and 10.00%~35.00%, respectively in 7 chemotherapeutical agents and 6 com-bined regimens, such as PTX (51.45%), TXT (20.29%), DDP (18.57%), TPT (11.63%), ADM (11.43%)and GEM(8.82%), as well as Vp 16 (6.25%). The PTX(51.45%) was the most sensitive agent for ovarianepithelial carcinoma compared with other 6 agents, especially the last 4, with a statistical significance(P<0.05) and TPT+PTX+DDP(35.00%), 8PTX+DDP(30.00%) as well as 4 others. TXT+DDP (20.59%)TPT+DDP (17.65%); GEM+DDP (11.76%), Vp 16 +ADM (10.00%). In the study, there was no correlationbetween the pharmaceutical inhibition ratio and the fact whether or not the drug has been used. The invivo, sensitive and drug-fast coincident rate was 72.86% (51/70) and the discrepancy was 27.14%(19/70). There was a statistical significance (P<0.05) between the overall coincidence and the discrepancy. Conclusion : The MTT assay in vitro has a referenced value for the individualized regimens on ovarianepithelioma and can, to some extent, direct the clinical medication.