18例颞叶神经节细胞胶质瘤的临床特点及手术疗效

The Clinical Characteristics and The Postoperative course of 18 Patients with Temporal Lobe Gangliogliomas

  • 摘要: 目的 :总结颞叶神经节细胞胶质瘤的临床特征及外科疗效。 方法 :回顾性分析四川大学华西医院1998年9月~2004年11月经手术后病理证实的患者临床资料。对患者进行了平均30个月的随访。 结果 :18例患者纳入本研究,其中包括14位男性和4位女性,手术时年龄从4到34岁(平均17.6岁)。所有患者均施行了至少一种手术方式。15例病理证实为WHOⅠ级,3例为WHOⅡ级。术后未见肿瘤复发,癫痫控制率达到84%。 结论 :颞叶神经节细胞胶质瘤患者临床症状以先兆、复杂性部分癫痫发作为最常见症状。随访显示,术后患者癫痫症状得到较好控制。肿瘤复发和恶性变风险较低。

     

    Abstract: Objective :To review the clinical features and surgical treatment for patients with tem-poral lobe gangliogliomas. Methods :Patients with temporal lobe gangliogliomas who underwent resec-tion of temporal lobe tumors, confirmed by surgical pathology, seen between September 1998 andNovember 2004 at the West China hospital, were selected. Medical records were reviewed for age at di-agnosis, age at onset of seizures, delay between seizure onset and tumor diagnosis, types and frequen-cies of seizures, EEG results, extent of surgery, and pathologic diagnosis. The follow- up period variedfrom 12 to 60 months (mean 30 months). Results :Eighteen patients were identified, including 13 malesand 5 females. The patients' age at surgery ranged from 4 to 34 years (mean 17.6 years). All patientsunderwent at least one surgical procedure. Fifteen cases were classified as WHO Grade Ⅰ lesions, and3 as WHO Grade Ⅱ lesions. None of the patients experienced recurrence. Among all patients the con-trol rate of seizure amounted to 84%. Conclusions :Complex partial seizures and auras are the commonpresenting symptom of these patients. Follow-up suggests patients will achieve relief from the seizuresafter surgery and have a low risk for tumor recurrence and malignant progression.

     

/

返回文章
返回