Abstract: Metastatic neoplasm of liver is common, 35 to 50 percent of which is from abdomen carcinoma. It has some special character in iconography. Recent years, the application of operation, intervention and three dimensional-stereotactic radiotherapy makes further progression in its treatment. While, chemotherapy still plays the dominant role. The first -line regimen includes FOLFOX、 FOLFIRI、and IFL combined with AVASTIN etc. Further more, molecular target therapy such as AVASTIN and ERBITUX is the latest research. These drugs benefit the survival of advanced colorectal carcinoma patients, which also ensures its newposition in treatment.