保留部分前列腺包膜在全膀胱切除原位回肠新膀胱术中的应用

Application of Partial Prostate Capsule Sparing in Radical Cystectomyand In Situ Ileal Neobladder for Bladder Cancer

  • 摘要: 目的:探讨传统全膀胱根治术及改良保留部分前列腺包膜全膀胱切除术对浸润性膀胱癌的疗效。方法:收集2000年1月~2006年1月膀胱癌行根治性全膀胱切除术45例,男性,平均年龄59岁,26例行传统全膀胱切除术,19例行改良保留部分前列腺包膜全膀胱切除术,随访观察手术效果及生活质量。结果:术后病理报告T2aN0M026例,T2bN0M016例,T3aN0M03例。平均随访39个月,改良组无瘤生存19例,传统组无瘤生存23例,带瘤生存1例,死亡2例。改良组及传统组白天控尿率分别为100%和73%,夜间尿失禁10%和50%。改良组术后81%保留勃起功能,传统组仅14.3%。全部患者储尿囊容量350~480ml,充盈压13~25cmH2O,残余尿量10~60ml。结论:对有选择的病例行保留部分前列腺包膜的全膀胱切除原位回肠新膀胱术可以更好地保留勃起和控尿功能。

     

    Abstract: Objective: To compare the effects of radical removal of the bladder and modified cystectomy with partial prostate capsule sparing, and to examine the standard procedure of orthotopic bladder replacement for bladder cancer. Methods: Data of 45 cases with radical removal of the bladder because of bladder cancer, during a period between January 2000 and January 2006, were collected. All patients were male, with a mean age of 59 years. Among the cases, traditional radical removal of the total bladder was conducted in 26 cases (traditional treatment group, TT group) and in situ ileal cystectomy with partial prostate capsule sparing was conducted in 19 cases (modified treatment group, MT group). The surgical results and quality of life were analyzed. Results: The results of pathological report were as follows: T2aN0M0 was found in 26 cases, T2bN0M0 was found in 16 cases, and T3aN0M0 was found in 3 cases. The mean follow-up period of the patients was 39 months. There were 19 cases with disease-free survival in the MT group, and there were 23 in the TT group. Metastasis was observed in 1 case and mortality in 2. In the MT and the TT group, the rate of urinary continence during the day was 100% and 73%, and that during the night was 10% and 50%, respectively. Conservation of erectile function occurred in 81% and 14.3% of the cases in the two groups, respectively. In all patients, capacity of the urinary vesicle ranged from 350 to 480 ml, filling pressure was 13 to 25 cm H2O, and the residual urinary volume was 16 to 60 ml. Conclusion: Radical cystectomy with partial prostatic capsule sparing and orthotopic neobladder in selected patients can improve sexual function and urinary continence.

     

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