Abstract:
Objective: To compare the effects of radical removal of the bladder and modified cystectomy with partial prostate capsule sparing, and to examine the standard procedure of orthotopic bladder replacement for bladder cancer. Methods: Data of 45 cases with radical removal of the bladder because of bladder cancer, during a period between January 2000 and January 2006, were collected. All patients were male, with a mean age of 59 years. Among the cases, traditional radical removal of the total bladder was conducted in 26 cases (traditional treatment group, TT group) and in situ ileal cystectomy with partial prostate capsule sparing was conducted in 19 cases (modified treatment group, MT group). The surgical results and quality of life were analyzed. Results: The results of pathological report were as follows: T
2aN
0M
0 was found in 26 cases, T
2bN
0M
0 was found in 16 cases, and T
3aN
0M
0 was found in 3 cases. The mean follow-up period of the patients was 39 months. There were 19 cases with disease-free survival in the MT group, and there were 23 in the TT group. Metastasis was observed in 1 case and mortality in 2. In the MT and the TT group, the rate of urinary continence during the day was 100% and 73%, and that during the night was 10% and 50%, respectively. Conservation of erectile function occurred in 81% and 14.3% of the cases in the two groups, respectively. In all patients, capacity of the urinary vesicle ranged from 350 to 480 ml, filling pressure was 13 to 25 cm H
2O, and the residual urinary volume was 16 to 60 ml. Conclusion: Radical cystectomy with partial prostatic capsule sparing and orthotopic neobladder in selected patients can improve sexual function and urinary continence.