Abstract: Objective: To study the biological characteristics, therapeutic methods and prognosis of male breast cancer cases. Methods: A total of 34 cases with male breast cancer were retrospectively reviewed. All of the patients were diagnosed and treated in our hospital during the period from 1980 to2005. Kaplan-Meier Product Limit method was used to calculate the survival rate and to draw the sur-vival curve. Results: Pathological TNM stage of the patients was as follows: there were 6 patients with Stage-Ⅰ breast cancer, 24 with Stage Ⅱ and 4 with Stage Ⅲ. A positive lymph node was found in35.3% of the patients. All patients received a modified radical mastectomy. The 5-year survival ratewas 65.3%. Conclusions: Male breast cancer has special biological features. Systemic treatment is rec-ommended for these patients, with modified radical mastectomy as the surgical treatment of choice.TNM stage and status of hormone receptor are the major prognostic factors.