Abstract: Objective :To study the factors affecting the prognosis of patients with lung cancertreated by sleeve lobectomy. Methods :One hundred forty-three patients with lung cancer underwentsleeve lobectomy. All cases were followed up after surgery. The findings related to prognosis were ana-lyzed by the life table method. The Log-Rank test was used to analyze the relationship between differ-ent stages and the prognosis after sleeve lobectomy. Results :The cohort included 42 cases (29.37%) ofstage Ⅰ (ⅠA and ⅠB) disease, 66 cases (46.15%) of stage Ⅱ (ⅡA and ⅡB) disease, 32 cases(22.38%) of stage ⅢA disease and 3 cases (2.09%) of stage ⅢB disease. The overall 5-year survivalrate was 47.20%. The 5-year survival rate in stage Ⅰ, stage Ⅱ and stage Ⅲ was 77.3%, 56.1% and20.56%, respectively. There was a significant difference between stage Ⅰ and stage Ⅱ when comparedindividually to stage Ⅲ, but there was no difference between stage Ⅰ and stage Ⅱ. The prognosis wasrelated to the N staging. The results showed that the 5-year survival rate in N₀ stage (73 cases,51.05%) and N₁ stage (56 cases, 39.16%) was 61% and 45%, respectively. However, no patients with N₂ stage (14 cases, 9.79%) survived more than 5 years. There was a significant difference in the 5-yearsurvival rate between N₀, N₁ and N₂ stages. Conclusion :Sleeve lobectomy is an effective method fortreating stage N₀ and N₁ lesions of primary lung cancer after careful preoperative screening of the cases.Surgical treatment after multidisciplinary adjunctive therapy is recommended for patients with stage-N₂ lesions.