Abstract:
Objective To investigate the effect of endoscopic breast reconstruction surgery under CO2 gas chamber on the perioperative blood gas parameters of patients with benign and malignant breast tumors and to ensure its safety.
Methods A total of 35 patients with benign and malignant breast tumors who underwent breast endoscopic surgery at Tianjin Medical University Cancer Institute & Hospital between March 2022 and September 2022 were selected. Blood was collected from the patients’ radial artery preoperatively (before CO2 aeration), during surgery (60 min after CO2 aeration), and postoperatively (30 min after anesthesia recovery). The changes in blood gas indices, including pH, arterial partial pressure of carbon dioxide (pCO2), residual alkali (±BE), and bicarbonate ion (HCO3-) and the correlations among them were analyzed statistically.
Results The intraoperative levels of pCO2 increased compared to the preoperative levels, while the postoperative levels of pCO2 reduced to the preoperative levels. Results from the t-test showed that the measurements of intraoperative pCO2 and HCO3− significantly increased compared with those postoperatively (t =−7.196, t =−4.709, all P<0.05). The pH value significantly decreased (t=7.069, P<0.05), and the positive BE value increased (t=−1.924, P>0.05). No significant changes in the preoperative measurements of pCO2, pH, and HCO3− relative to those postoperatively were observed (t=0.141, t=1.170, t=1.622, all P>0.05), while the negative BE value increased (t=1.830, P>0.05). Results from the Pearson correlation showed that the changes in pCO2 during surgery were correlated with the changes in pH and HCO3− (r=0.423, r=0.769, all P<0.05), while BE was correlated with HCO3− (r=0.678, P<0.05).
Conclusions Endoscopic breast reconstruction surgery under CO2 gas chamber impacted the patients’ perioperative blood gas analysis indices; however, the measurements returned to preoperative levels after recovery from anesthesia. Our findings suggest that endoscopic breast surgery under CO2 gas chamber reconstruction is safe and reliable, and thus, should be promoted.