Abstract: Objective: To study the prognostic factors and stereologic parameter Sv and Vv in node-positive breast inventive ductal carcinoma, so as to identify a independent numbers pattern for the prognosis. Methods: The Sv and Vv of 206 cases node-positive breast invasive ductal carcinomas havebeen measured. Results: Sv. <4.4,89 (89/114)cases have survived 5 -year,and Sv >5.5,71 (71/92)cases have died in 5-year. Conclusions: The measurement of the Sv (the surf ace area density of carcinoma) of breast invasive ductal carcinomas is a easy stereologic method and the parameters could be counted. As a importent guideline that can refect 5-year survive situation.