姚青, 凌瑞, 王岭, 袁时芳, 陈江浩, 马中, 易军, 张聚良, 云军, 杨华. 高龄乳腺癌患者术后早期应用多西他赛辅助化疗的安全性观察[J]. 中国肿瘤临床, 2004, 31(7): 395-397.
引用本文: 姚青, 凌瑞, 王岭, 袁时芳, 陈江浩, 马中, 易军, 张聚良, 云军, 杨华. 高龄乳腺癌患者术后早期应用多西他赛辅助化疗的安全性观察[J]. 中国肿瘤临床, 2004, 31(7): 395-397.
shu
Yao Qing, Ling Rui, Wang Ling, . Safety of Docetaxel Administered on Elder Patients with Weekly Schedule at Early Stage Following Mammectomy[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2004, 31(7): 395-397.
Citation: Yao Qing, Ling Rui, Wang Ling, . Safety of Docetaxel Administered on Elder Patients with Weekly Schedule at Early Stage Following Mammectomy[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2004, 31(7): 395-397.
shu

高龄乳腺癌患者术后早期应用多西他赛辅助化疗的安全性观察

Safety of Docetaxel Administered on Elder Patients with Weekly Schedule at Early Stage Following Mammectomy

    摘要
  • 摘要: 目的:探讨高龄乳腺癌患者术后早期应用多西他赛(多西紫杉醇)每周方案辅助化疗的安全性.方法:62例≥70岁的Ⅱ期乳腺癌患者术后随机分为两组,分别于术后第3天和14天开始应用多西他赛每周方案辅助化疗,观察其对切口愈合、化疗全身反应和血清IL-2,sIL-2R的影响.结果:两组切口愈合状况和消化道反应无明显差异,白细胞水平下降均不显著.术后两组IL-2,sIL-2R的变化趋势相同.结论:高龄乳腺癌患者术后早期应用多西他赛每周方案辅助化疗,具有良好的安全性,对患者的免疫功能影响不大.

     

    Abstract: Objective: To evaluate the safety of docetaxel administered on elder patients with weekly schedule at early stage following mammectomy. Methods: 62 patients with stage II breast can-cer, aged more than 70, were divided into 2 groups at random. Doxetaxel was applied on the 3rd and 14th day respectively after operation. Affection on healing of incision, response to chemotherapy and serum IL-2, sIL-2R were investigated. Results: No evident difference in incision healing or response of digestive tract between the two groups were observed. No marked decrease was observed in the number of white blood cells. Change of serum IL-2, sIL-2R appeared to be similar in two groups. Conclusion:Safety is warranted on elder patients administered of docetaxel with weekly schedule at early stage fol-lowing mammectomy. No significant affection is found on the immunity function of patients.

     

    • HTML全文
    • 参考文献(1)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回